Understanding Your Puppy’s Vaccination Schedule

Tipsy Rabbit's Tips & Pointers Blog

Strong Foundations Begin with Smart Choices

As a breeder, I’m deeply committed to educating our families and giving each of our puppies the very best start—both in life and in their new homes. That includes making informed decisions about vaccination. While vaccines are a vital part of protecting puppies from preventable diseases, timing is everything—and often one of the most misunderstood pieces of the puzzle.

Puppies receive maternal antibodies through nursing, which can interfere with the effectiveness of early vaccinations if given too soon. That’s why we follow a carefully considered vaccination schedule and advocate against over-vaccinating. It’s not just about checking boxes—it’s about supporting your puppy’s long-term health, building a strong immune foundation, and helping families make confident, informed choices from the start.

Newborn puppies receive temporary immunity from their mother’s milk—specifically through colostrum, which is rich in protective antibodies. These maternal antibodies offer vital protection during the early weeks of life, but they can also interfere with the effectiveness of vaccines if given too early.  For many years, vaccine protocols started at 6 weeks of age, but current research shows this timing may be too early, as maternal antibodies can block the vaccine from building true immunity.

Today’s veterinary guidance supports beginning the DHPP vaccine series at 8 weeks, when maternal immunity is beginning to wane and the puppy’s immune system is ready to respond effectively. This adjustment gives your puppy the best chance to build strong, lasting protection.

At Tipsy Rabbit, we believe in striking a balance between veterinary best practices and thoughtful customization. Every puppy is different, and vaccine decisions should reflect their unique health profile, environment, and lifestyle. Below is our recommended vaccination schedule, along with important notes to help guide your conversations with your veterinarian.

Tipsy Rabbit's Recommended Vaccination Schedule

8 Weeks (First Vet Visit After Go-Home)- DHPP Vaccine 1 of 4

10–12 Weeks - DHPP 2 of 4

14–16 Weeks - DHPP 3 of 4

18-20 Weeks - DHPP 4 of 4 AND Rabies Vaccine (Required by law)

Leptospirosis and additional vaccines such as Bordetella & Canine Influenza may be discussed with your vet.

Tipsy Rabbit Vaccine Caution & Customization Notes

While Leptospirosis is now generally considered a core vaccine, we still recommend spacing it out from other core vaccines like DHPP & Rabies whenever possible. This helps minimize stress on the immune system and makes it easier to identify the source of any reaction.

Valley, one of our own girls, is a great example. She experienced a mild reaction after each of her Lepto doses. Thanks to spacing out her vaccines, we were able to pinpoint the cause and now pre-treat with a small dose of Benadryl beforehand—an easy adjustment that keeps her protected and comfortable.

We also recommend requesting the intranasal form of the Bordetella vaccine rather than the injectable. The nasal version tends to be better tolerated and offers faster, localized immunity—especially helpful for puppies entering training, boarding, or grooming environments.

Based on our lifestyle, our travel arrangements with the dogs, guidance from our trusted family veterinarian, and a personal commitment to avoiding unnecessary vaccinations, we have chosen not to vaccinate our dogs for Canine Influenza. We encourage each family to thoughtfully weigh the pros and cons of this vaccine and make an informed decision that aligns with your individual needs, environment, and veterinary advice.

Looking Ahead: The Long-Term Vaccine Plan

After your puppy completes the initial vaccine series and receives the 1-year booster, many veterinarians shift to a 3-year DHPP schedule. Current research supports this extended immunity, meaning adult dogs are often well-protected for several years after their booster. Always consult with your veterinarian to confirm what’s best for your dog based on their exposure and lifestyle.

Have Questions About Vaccinations?

We’re always happy to share what vaccinations we give our own dogs and how we approach long-term care for our TopPups. We also encourage every family to do their own research before heading to the vet so you can ask informed questions and make choices tailored to your dog—not just based on the clinic’s standard protocol.

Because Every TopPup Deserves the Best Start ❤️

At Tipsy Rabbit, we believe raising a healthy, confident puppy begins with informed, intentional decisions—and that includes their veterinary care. Understanding your puppy’s vaccine schedule helps you advocate for their needs while setting them up for a lifetime of love, adventure, and good health. 

Cheers to Happy Tails and Healthy Starts!

📸 Featured TopDog: Alvarado Farm's Lady Raben-Valentinstag Call Name: Valley